Metabolic Assessment Profile

Posted On: February 25, 2017

Well, after a little hiatus, I’m finally back to my studies with FDN.  My most recent lesson was in learning about how to use the BioHealth 101 Metabolic Assessment Profile.  In previous posts, I’ve shown you how we can asses how you’re handling your stress and how your hormones are balancing out via the BioHealth 205.  Now we get to look at how you’re managing digestion of proteins, dealing with oxidative stress and detoxifying.


At FDN, we do not simply give a series of tests.   FDN is a new way of thinking about the human body.  We seek the underlying causes of metabolic chaos:  imbalances, deficiencies, and/or overburden.  Working at the deepest level possible, we restore balance, healing and function to the way it was intended to be.  The human body has wonderful innate wisdom and desire to thrive; we coach up that “Vital Reserve.”


The Metabolic Assessment Profile looks at the values that will provide insights into various healing opportunities, and help guide natural therapies when there is a clinical correlation with the individual’s symptoms.  We absolutely never treat the test results, we treat the person, how they feel, and see if their test results correlate before recommending any kind of therapy.  Often the test results simply points us in the direction of doing further investigation.

There are three values given in the urine test from the BH101:

  • Urinary Indicans
  • Urinary Lipid Peroxidases
  • Urinary Bile Acids

A positive indican will show up on your results if there is improper digestive breakdown of proteins.  This could stem from a lack of enzymes, hydrochloric acid, or even infection.  Stress, age, improper nutrition, etc. can all be contributors to a positive indican.  You might be presenting with gas, bloating, diarrhea/constipation, indigestion, etc. If you are having a hard time digesting animal protein, you will likely find a positive indican in your test result.  When you can’t assimilate your proteins well, you will be lacking in amino acids.  These are the basic building blocks for all the cells in your body, including muscle and bone mass, as well as creation of neurotransmitters.  In fact, you may find that foggy thinking is one symptom you are dealing with.  We need proper assimilation of amino acids (protein) to create the enzymes needed to power many chemical reactions in the body, as well as create hemoglobin to carry oxygen in your blood.

When there is a lack of enzymes and good bacteria to break down proteins and allow for assimilation through the small intestine, the proteins may be acted upon by anaerobic bacteria which then cause putrefaction.  This is how indoles are produced (nasty smelling organic compounds).  If not properly excreted through the feces, indoles are recirculated through the hepatic portal system, metabolized by the liver, and excreted as indican in the urine.  So if you have high positive indicans, we know that you are lacking sufficient ability to breakdown your proteins.

Possible Causes and Effects of Positive Indicans:

  • Hypochlorhydria (insufficient HCl, pepsin)
  • Pancreatic insufficiency, trypsin, chymotrypsin
  • Food sensitivities
  • Parasites
  • Overgrowth of anaerobic bacteria/dysbiosis
  • Bacterial infection (ex: H.pylori)
  • Fungi
  • Hypermotility (rapid transit time)
  • SIBO, leaky gut, biofilm formation

Treatment would include addressing changes to diet appropriate to the patient, using more bioavailable forms of proteins, and working on gut healing protocols.


Lipid Peroxidases are an indication of oxidative stress and free radical damage.  It’s basically the oxidative degradation of lipids which form cell membranes.  Free radicals steal electrons from the lipids in the cell membrane which results in cell damage.  A high value here could result in cancer, accelerated aging, and immune deficits.  A high LP might be found in someone who is getting sick often, has low energy, is achy, etc.  While oxidative stress is a natural part of life and the life cycle of all our cells, there is a limit to how much toxic load our bodies can handle.  Excessive oxidative stress will lead to the cascade of metabolic chaos.

Causes and Effects of Elevated LP:

  • Exposure to toxins, chemicals and/or heavy metals
  • Exposure to pathogens and their excretions
  • Over-exercise
  • Symptoms include fatigue, memory loss, muscle/joint pain, advanced aging, impaired eyesight, headaches, and susceptibility to infections

Treatment would include the addition of antioxidant-rich foods, limit to exposure of environmental toxins, and moderating exercise.  It would also be prudent to investigate possible cardiovascular disease and cancer.

Urinary Bile Acids in excess show that overall detoxification is compromised.  A congested liver, poor fat metabolism, impaired enterohepatic circulation (bile salt secretion from the liver to the intestine), excessive environmental or general toxin load, liver disease, or infection can all be related to excessive UBAs in the test results.  The main detoxification organs of the body are the liver, colon, skin, lymph, lungs, and kidneys.  However, if the liver is compromised, the whole detoxification system suffers.

The liver has many important functions, but filtration is its primary one.  Good nutrition and hydration allows the liver to filter blood efficiently.  In Phase I of detoxification, the body uses enzymes and nutrients to neutralize toxins into water-soluble compounds.  At this point toxin reactivity actually increases, but is then moved into Phase II.  During Phase II, amino acids (again we need this from protein breakdown) are attached to the toxins to further neutralize them and escort them out of the body.  Lastly, elimination takes place either through the digestive tract via bile or via the kidneys in the urine.

Bile acids, which make up 80% of one’s bile, are made in the liver, stored in the gallbladder, secreted into the intestines and are partially recirculated back to the liver.  Some bile is naturally lost via normal excretion through the bowels.  A healthy liver would easily replenish these bile acids.  The urinary bile acid levels indicate how much is spilling over into general circulation.  A high UBA level indicates a compromised detoxification system.  

Urinary bile acids in excess show that there is compromised liver and gallbladder function, as well as enterohepatic circulation of bile.  A congested liver, infection, missing or congested gallbladder, and/or poor intestinal and enterohepatic circulation of bile will all lead to inadequate bile acid recovery.  The BH101 will show both high or low UBA levels, and allow one to see if further discovery is necessary.

Causes and Effects of High/Low UBA Levels:

  • Liver congestion or disease
  • May present with unstable blood sugar levels
  • May have a hard time loosing weight or have sluggish metabolism
  • Blood panel may show elevated LDl, triglycerides, low HDl
  • Can cause indigestion and putrid body odor
  • Likely have intolerance to alcohol, dietary fats
  • May have headaches and be prone to depression/irritability

Therapy would include liver support through milk thistle, glutathione, n-acetyl-cysteine and bioflavonoids.  Liver flushing, gallbladder support , digestive support, and ox bile would also be considered.  It would be ideal to look for possible pathogens and liver disease.  Low UBA would indicate investigation into possible cirrhosis, gallbladder dysfunction, and enterohepatic circulation of bile.


I know today’s post got a little overly technical, but I really needed to be able to explain this to you, so I could better understand how this very simple test can show issues with such a complex system.  If you feel like you are in need to further investigation into your own detoxification system, please contact an FDN practitioner near you.  I very much look forward to finishing my studies to be able to walk you through the process myself.  


Yours in Health, 



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